After explaining the results of your assessment, the genetics specialist may recommend you have testing to check for a genetic abnormality linked to kidney cancer.
GENETIC TESTING MAY BE SUGGESTED, ESPECIALLY IF YOU HAVE:
It will still be up to you to decide whether or not you want to have genetic testing. If you do choose to have testing, the genetics professional will explain the results to you.
DEPENDING ON YOUR RISK OF DEVELOPING KIDNEY CANCER, YOUR DOCTOR MAY SUGGEST THAT YOU:
Sometimes when people with known genetic conditions are planning a family, they want to know if a child has inherited the gene mutation. Prenatal tests are available at various stages of pregnancy for couples who are interested in knowing this information. For couples who are not willing to take the chance of having a child with one of these conditions, in vitro fertilization (IVF) with preimplantation genetic diagnosis (PGD) may be an option. In some instances, genetic testing can be performed on embryos created through IVF, with only those embryos not having the condition being implanted back into the woman’s womb (uterus). There are risks and benefits associated with all of these choices and there may be some costs associated with these procedures. Genetic counsellors are the ideal healthcare professionals to provide potential parents with information about these tests.
- Genes, genetics and kidney cancer
- Family history and hereditary kidney cancer
- Inherited disorders that increase kidney cancer risk
- Assessing genetic risk and genetic counselling
Canadian Cancer Society. Genetic Testing. 2016.
Hampel H, Bennett RL, Buchanan A, et al. A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment. Genetics in Medicine. 2015; Jan;17(1):70-87.
Ho TH, Jonasch E. Genetic Kidney Cancer Syndromes. Journal of the National Comprehensive Cancer Network. 2014; September;12(9):1347-1355.
Lattouf JB, Pautler SE, Reaume MN, Eva ,et al. Structured assessment and followup for patients with hereditary kidney tumour syndromes. Canadian Urological Association Journal. 2016; 10(7-8):E214-22.
National Cancer Institute. Genetic Testing for Hereditary Cancer Syndromes. 04/11/2013.
National Cancer Institute. Genetics of Kidney Cancer (Renal Cell Cancer) (PDQ®) – Health Professional Version. Updated: 10/13/2016.
Reaume MN, Graham GE, Tomiak Eva, et al. Canadian guideline on genetic screening for hereditary renal cell cancers. Canadian Urological Association Journal. 2013; 7(9-10):319-323.
U.S. National Library of Medicine. Genetics Home Reference: Your Guide to Understanding Genetic Conditions. Help Me Understand Genetics. Published: 12/1/2016.