Effectiveness of Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy
[vc_row][vc_column][vc_column_text css=""] Background: Nivolumab (Opdivo®) is an immunotherapy drug that is already approved for the treatment of kidney cancer in Canada. This drug stimulates the immune system to attack any cancer cells that remain by targeting a molecule called PD-1. The Trial: This trial will investigate whether adding nivolumab...
Combination Chemotherapy With or Without Radiation for Advanced Wilms’ Tumor
[vc_row][vc_column][vc_column_text css=""] Background: Wilms’ tumor is a type of kidney cancer that mostly affects children. This study is for patients who have been recently diagnosed with stage III or stage IV Wilms’ tumor, which means the cancer has spread beyond the kidney. Chemotherapy uses strong medicines to kill...
A Study of Post-Surgery Treatment Options for Children With Stage I–III Wilms’ Tumor
[vc_row][vc_column][vc_column_text css=""] Background: Chemotherapy uses strong medicines to kill cancer cells or stop them from growing. In this study, patients may receive several different chemotherapy drugs that work in different ways. Vincristine stops cancer cells from dividing and spreading. Dactinomycin blocks the instructions cancer cells need to...
A Study of V940 (Cancer Vaccine) and Pembrolizumab After Surgery for Clear Cell and Papillary Kidney Cancer (INTerpath-004)
[vc_row][vc_column][vc_column_text css=""] Background: Intismeran autogene (V940/mRNA-4157) is a personalized cancer vaccine made using mRNA technology, designed to help the immune system recognize and fight the patient’s specific cancer. Pembrolizumab (Keytruda®) is an immunotherapy drug that is already approved for the treatment of kidney cancer in Canada. It works...